BREAKING

Friday, April 25, 2025

Silent Threat on the Dinner Table: UP Biologists Sound Alarm on Multidrug-Resistant Salmonella in Chicken


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Behind the comforting aroma of sizzling chicken lies a silent menace that could endanger millions—multidrug-resistant (MDR) Salmonella—lurking in one of the most consumed meats in the Philippines. In a groundbreaking and urgent revelation, biologists from the University of the Philippines Diliman – College of Science, Institute of Biology (UPD-CS IB) are now raising red flags over the alarming spread of these stealthy, drug-defiant pathogens through poultry sold in everyday wet markets across Metro Manila.

With food safety and public health hanging in the balance, the Pathogen-Host-Environment Interactions Research Laboratory (PHEIRL) of UPD-CS IB has uncovered findings that are as eye-opening as they are terrifying: Chicken meat, a staple on Filipino tables, is teeming with dangerous strains of Salmonella that can no longer be treated by multiple lines of antibiotics.

Led by researchers Michael Joseph Nagpala, Jonah Feliza Mora, Rance Derrick Pavon, and Dr. Windell Rivera, the team deployed state-of-the-art whole genome sequencing (WGS) and phenotypic antimicrobial resistance (AMR) testing to uncover the DNA-level secrets of the bacteria. What they found was chilling: high levels of MDR Salmonella strains, genetic evidence of resistance to 12 different drug classes, and 50 antimicrobial resistance genes (ARGs) within these pathogens—making them highly virulent and alarmingly persistent.


A Brewing Public Health Crisis

Salmonella infections are already notorious for causing diarrhea, abdominal cramps, fever, nausea, and vomiting—often striking victims within hours of consumption and lasting up to a week. But what happens when these bacteria can no longer be tamed by our most trusted medicines?

The research revealed Infantis as the most dominant strain among the samples, followed by Brancaster, Anatum, London, Uganda, and Derby—all possessing an arsenal of virulence and resistance genes. These strains are not just surviving—they’re evolving, acquiring resistance through mobile DNA called plasmids, and infiltrating the food chain with shocking ease.

According to the team, “Infections from MDR Salmonella, especially among vulnerable populations and from highly virulent serovars, can lead to life-threatening, systemic, and untreatable manifestations.”

In other words: this is not just about getting sick from undercooked chicken. This is about battling bacteria that could soon render our medical defenses useless.


Wet Markets: Ground Zero

Perhaps most alarming is the setting in which these MDR bacteria are thriving—local wet markets. Often overlooked in formal food safety regulation, these markets serve as major distribution points for raw meat, making them potential hotspots for bacterial cross-contamination. From the butcher’s blade to the consumer’s kitchen, every touchpoint becomes a transmission opportunity.

“This isn’t just about farms anymore,” warns the team. “There is a clear and significant risk of MDR Salmonella variants spreading within wet markets and food animal value chains, as well as cross-contamination and undetected transmission in kitchens and homes.”


A Call to Action: Policy, Awareness, and Research

The urgency of this situation cannot be overstated. The team calls for sweeping multi-sectoral reforms that cut across agriculture, health, and consumer behavior. These include:

Stricter regulations on the use of antibiotics in poultry farms

Surveillance and reporting systems for antimicrobial resistance

Education campaigns for farmers, vendors, and consumers on AMR and food hygiene

Research investment into alternatives to antibiotics and new treatments

National policies aligning with global food safety standards

The study, supported by the Department of Agriculture-Biotechnology Program Office, should serve as a wake-up call for all sectors. The Philippines cannot afford to let this biological threat fester unnoticed and unchecked.


The Invisible War

As families across the country prepare their favorite chicken adobo or inihaw na manok, the invisible war against superbugs continues in the background. This isn’t just a scientific study—it’s a warning siren. MDR Salmonella doesn’t just threaten our food—it endangers our future.


The Wazzup Pilipinas founder urges all stakeholders—from policy makers and food producers to everyday consumers—to treat this threat with the seriousness it demands. The time to act is now—before our antibiotics fail and a simple meal becomes a matter of life and death.

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